Jacksonville Indian Community - JacksonvilleIndian.com
| | | | | | | | | | |
 


 

High Vitamin D dose may rapidly cut arterial stiffness


United States,Health/Medicine


Author : Indo Asian News Service

Health/Medicine, United States Read Latest News and Articles

Share With Your Friends

Add To My Favorite     Add A Picture

Add an Article

View All Contributions

New York, Jan 3 (IANS) High-doses of Vitamin D can potentially reduce arterial stiffness -- a major risk factor for cardiovascular-related disease and death -- in young vitamin-deficient obese adults, researchers say.

Cardiovascular diseases are the leading cause of death globally, with an estimated 17.7 million deaths in 2015, and representing 31 per cent of all global deaths.

Rigid artery walls and Vitamin D deficiency might be the potential contributors, said Yanbin Dong, geneticist and cardiologist at the Augusta University, US.

The findings showed that the dose of 4,000 international units (IUs)-- more than six times the daily 600 IUs currently recommended for most adults and children -- now considered the highest, reduced arterial stiffness the most and the fastest, 10.4 per cent in four months.

Two thousand IUs decreased stiffness by two per cent in that timeframe.

"When your arteries are more stiff, you have higher pulse wave velocity, which increases your risk of cardiometabolic disease in the future," said Anas Raed, research resident at the varsity.

For the study, detailed in the journal PLOS ONE, the team looked at African-Americans aged 13-45 -- all of whom had some degree of arterial stiffness -- taking varying doses of the vitamin best known for its role in bone health.

While just how Vitamin D is good for our arteries is not completely understood, it appears to impact blood vessel health in many ways, the researchers said.

Laboratory studies have shown that mice missing a vitamin D receptor have higher activation of the renin-angiotensin-aldosterone system, activation of which increases blood vessel constriction, that can contribute to arterial stiffness.

Vitamin D also can suppress vascular smooth muscle cell proliferation, activation of garbage-eating macrophages and calcification formation, all of which can thicken blood vessel walls and hinder flexibility.

Vitamin D also reduces inflammation, an underlying mechanism for obesity related development of coronary artery disease, Raed said.

--IANS

rt/ksk/vm



Latest Showbiz News

View More News


More News Articles

On World Music Day, singing legend Lata Mangeshkar's tips to singers

Kejriwal unwell, to go to Bengaluru

Tamil Nadu girl Anukreethy Vas wins Miss India World 2018 title

Rajasthan CM, Ramdev to celebrate Yoga Day with 2 lakh

Alia's 'Raazi' mints over Rs 200 cr worldwide


Our website is made possible by displaying online advertisements to our visitors.
Please consider supporting us by disabling your ad blocker.